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	<title type="text">Thor Benson | The Verge</title>
	<subtitle type="text">The Verge is about technology and how it makes us feel. Founded in 2011, we offer our audience everything from breaking news to reviews to award-winning features and investigations, on our site, in video, and in podcasts.</subtitle>

	<updated>2015-11-11T14:30:02+00:00</updated>

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		<entry>
			
			<author>
				<name>Thor Benson</name>
			</author>
			
			<title type="html"><![CDATA[How an illegal psychedelic drug could help treat opiate addiction]]></title>
			<link rel="alternate" type="text/html" href="https://www.theverge.com/2015/11/11/9700446/ibogaine-treatment-opiate-addiction-psychedelic-drug" />
			<id>https://www.theverge.com/2015/11/11/9700446/ibogaine-treatment-opiate-addiction-psychedelic-drug</id>
			<updated>2015-11-11T09:30:02-05:00</updated>
			<published>2015-11-11T09:30:02-05:00</published>
			<category scheme="https://www.theverge.com" term="Health" /><category scheme="https://www.theverge.com" term="Report" /><category scheme="https://www.theverge.com" term="Science" />
							<summary type="html"><![CDATA[Kevin is in the fetal position on a warm bed in Mexico, in the throes of opiate withdrawal. Suddenly, a buzzing noise enters his ear, as if a wasp is building a nest in there. It&#8217;s the first sign the ibogaine he just consumed is taking effect, and things are about to get weird. &#8220;This [&#8230;]]]></summary>
			
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<img alt="" data-caption="" data-portal-copyright="&lt;a href=&quot;https://www.flickr.com/photos/kaushiknarasimhan/5161019853/in/photolist-8S4zoV-wXveXe-2P2yRF-pmN9Lp-q28WoK-qggHps-53NF1V-d8Ggms-4zaxCh-k3qEoe-4KtntN-d8kB6-bEdZ6h-68AzVu-vmpJBU-3Dzc93-9dW8zw-9iME3b-hK6N1L-7svgys-PVLFS-ERGKm-98Sr8o-74hbvZ-5rtPii-fPs3U5-oaCp1z-EfUEe-sCAFa-rKoJGV-vacH8y-akW5D7-9WKkti-f3nupH-pmN9L4-66KLmg-aitkxg-q399M6-q1ZXcN-q27rR8-9dT4Ln-nHEVtP-qpD5Ym-9aRwv9-5h4qAU-7P2zdV-M4Hzv-7s4F3M-6N145y-98Sp5q&quot;&gt; Kaushik Narasimhan/Flickr&lt;/a&gt;" data-has-syndication-rights="1" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/15572361/5161019853_8a2d2a466d_o.0.0.1447119301.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<p>Kevin is in the fetal position on a warm bed in Mexico, in the throes of opiate withdrawal. Suddenly, a buzzing noise enters his ear, as if a wasp is building a nest in there. It&rsquo;s the first sign the ibogaine he just consumed is taking effect, and things are about to get weird.</p>

<p>&#8220;This really intense energy slowly began to build in the center of my body and permeated throughout,&#8221; Kevin tells <em>The Verge</em>, recalling that night. &#8220;It extended down to the tips of my toes and up to the crown of my head. While the physical sensation was building up, I had my eyes closed, and I started to feel this upward momentum within my mind.&#8221; He felt he was being shot up into space. There was a consistent buzzing noise growing louder and louder with each passing moment, until all perception of his body&rsquo;s location abruptly shattered. Then, he was captured in time and space like a photograph.</p>
<p><q class="right">The ibogaine was part of his chance to free himself from addiction</q>Kevin was a 24-year-old with an intense opiate addiction &mdash; heroin and OxyContin were his drugs of choice &mdash; at the time, and the ibogaine was part of his chance to free himself from the addiction. He tried the standard treatments, like rehab and the prescription drug Suboxone, but they weren&rsquo;t working for him. He then decided to enroll in a study evaluating the psychedelic substance ibogaine, for use in kicking an opiate addiction.</p>
<p>States across the US are facing <a href="http://theweek.com/articles/541564/how-american-opiate-epidemic-started-by-pharmaceutical-company">opiate epidemics</a>, which often start with prescription drugs, either legally prescribed or illegally bought. (Some people start taking opiates to treat legitimate pain and get addicted; some get pills from friends.) <a href="https://www.drugabuse.gov/about-nida/legislative-activities/testimony-to-congress/2015/americas-addiction-to-opioids-heroin-prescription-drug-abuse">Over 2 million</a> people in the US are addicted to opiates, and addiction is hard to treat. <a href="http://www.forbes.com/sites/cjarlotta/2015/01/16/deaths-involving-opioids-heroin-continue-to-rise-report-shows/">Data from the Centers for Disease Control</a> (CDC) shows there were 16,235 deaths from overdosing on prescription opioids and 8,257 deaths from heroin in 2013.</p>
<p><q class="left">There&#8217;s motivation in the medical community to improve addiction treatment &mdash; even if it means something kind of far out </q>Treatment for addiction varies widely, and is not very effective. Addicts may have to go through a <a href="http://www.health.harvard.edu/mind-and-mood/treating_opiate_addiction_detoxification_and_maintenance">supervised detox</a> from the drug, often lasting over a week. Sometimes they are then prescribed a drug, like methadone, to treat withdrawal &mdash; but sometimes they are simply put on an abstinence program in a rehab facility. Some facilities in the United States report treatment dropout rates as high as <a href="http://projects.huffingtonpost.com/dying-to-be-free-heroin-treatment">75 percent</a>; relapse rates for people who go through treatment can be as high as <a href="http://www.aafp.org/afp/2006/0501/p1513.html">90 percent</a>. So there&rsquo;s motivation for the medical community to try to improve addiction treatment, even if it means something kind of far out &mdash; like a psychedelic drug.</p>
<p>In fact, ibogaine, which is found in the root bark of some West African plants, isn&rsquo;t the only psychedelic substance that&rsquo;s being studied for addiction treatment. Psilocybin (perhaps better known as &#8220;magic mushrooms&#8221;), for instance, appears to help treat smoking addiction and alcoholism. <a href="http://hub.jhu.edu/2014/09/11/magic-mushrooms-smoking">In a study</a> published last year from John Hopkins University, 12 of 15 longtime smokers were able to quit with the help of the substance. <a href="http://www.scpr.org/news/2014/05/19/44153/psychedelic-science-researches-enlist-psilocybin-t/">A 2014 study</a> from researchers at the University of New Mexico focused on 10 participants and found drinking can be reduced by up to 50 percent with psilocybin treatment.</p>

<p>Ibogaine became a Schedule I substance in 1970, meaning it is said to have no &#8220;currently accepted medical use and a high potential for abuse,&#8221; and it was batted about as an anti-abuse drug shortly before that. The possibility of using the drug for treating addiction became known <a href="http://america.aljazeera.com/watch/shows/america-tonight/articles/2014/5/19/could-this-a-miracleadrughelpmillionsofamericanaddicts.html">a few years before</a>, when a spry 19-year-old heroin addict named Howard Lotsof tried the drug in 1962. He was just looking for another way to get high, but it changed him. &#8220;The next thing I knew,&#8221; he <a href="http://www.nytimes.com/2010/02/17/us/17lotsof.html">told <em>The New York Times</em></a> in 1994, &#8220;I was straight.&#8221; He gave it to six other heroin addict friends, and five of them quit heroin immediately. Lotsof advocated for using ibogaine to treat opiate addiction for the rest of his life. He started the Dora Weiner Foundation to educate people on the drug and push for studies around the world, and he was successful at getting trials started <a href="http://www.bbc.com/news/magazine-17666589">in the Netherlands</a>.</p>
<p><q class="center">Ibogaine is illegal; that&#8217;s slowed the research process</q></p>
<p>But ibogaine is illegal, and that&rsquo;s slowed research progress. Certain underground trials that were done by various unaffiliated researchers in the US in the 1970s <a href="http://america.aljazeera.com/watch/shows/america-tonight/articles/2014/5/19/could-this-a-miracleadrughelpmillionsofamericanaddicts.html">led to deaths</a>. But Lotsof did get the National Institute on Drug Abuse to research ibogaine, and he received approval for an FDA clinical trial. Unfortunately for Lotsof, the study was never done, due to a lack of funding.</p>

<p>Actually, ibogaine research isn&rsquo;t without encouragement in the mainstream. Mark Parrino, president of the American Association for the Treatment of Opioid Dependence (AATOD), believes there could be a place for ibogaine in opiate addiction treatment. Since opiate addictions are so difficult to treat, doctors are desperate for anything that might work. &#8220;It&rsquo;s not a widely used medication, but the general view is that if it has some helpful approach for some people who don&rsquo;t want to be using one of the three federally approved medications, that&rsquo;s great,&#8221; he tells <em>The Verge</em>. Kevin is one of those people.</p>
<img src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/4249347/16947134920_93ac8d1293_o.0-rotated.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="" title="" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p><em><em>Jeff Djevdet (Flickr)</em></em></p>

<p>Around 2009, while Kevin was finishing college, he started casually taking pills like Percocet, Roxycodones, and OxyContin. A year later, he was cutting up pills and snorting them. Kevin&rsquo;s addiction became bad enough that he dropped out of his undergraduate program Northeastern University. (He returned to school and did eventually graduate, in 2013.) By June 2010, he was doing heroin. &#8220;I was just shooting speed balls and kind of entering a psychotic state,&#8221; he said. He eventually ended up getting arrested while shoplifting. He decided to go to rehab for 30 days, followed by some 12-step meetings. He began using heroin again shortly after he was released.</p>

<p>For about a year, he didn&rsquo;t have a job &mdash; he just did drugs. Eventually, his mother convinced him to look into experimental ibogaine treatments. So Kevin went to Southern California and met with Thomas Brown, the leader of the ibogaine study, in the summer of 2011.</p>

<p>Thirty people were enrolled in the study, and 12 made it to the end a year later, says Brown, who&rsquo;s a research coordinator at the University of California&ndash;San Diego. That&rsquo;s a high drop-out rate, in part because many patients lost contact with researchers once treatment was over. Preliminary data shows most people will relapse. Brown argues that may be because the treatment didn&rsquo;t include any mandatory aftercare, like therapy or a halfway house. This kind of support is important for addicts, because it&rsquo;s easy for them to fall back into old habits without direct support in the first few months after treatment. Most patients only stayed at the clinic about a week after the study treatment, and were clean for that time &mdash; and for at least a week after.</p>
<p><q class="left">Preliminary data shows most people will relapse</q>&#8220;It does interrupt the addiction for people,&#8221; Brown says. But Brown isn&rsquo;t presenting ibogaine as a cure for addiction. (The results suggest that ibogaine alone isn&#8217;t enough, anyway.) Rather, he thinks it gives patients a separation from toxic mental patterns and lessens withdrawal &mdash; which might allow conventional treatments to work better.</p>
<p>Kevin&rsquo;s treatment began with an intake interview with Brown, followed by some EKGs and other tests. Around 10PM he received the ibogaine &mdash; three doses in a pill form, spaced a few minutes apart. The Multidisciplinary Association for Psychedelic Studies, which sponsored the trial did not provide the drugs; they are managed by the Pangea Biomedics ibogaine clinic in Baja California, Mexico.The researchers observed the treatment in the clinic.</p>

<p>Kevin was supposed to wait until he had hit the peak of his opiate withdrawal, an evaluation he was to make, to start the treatment, but he was too eager and started before that. &#8220;It didn&rsquo;t entirely bring me through the withdrawal, but I don&rsquo;t blame the medicine for that,&#8221; he says. &#8220;I blame myself for rushing the treatment.&#8221; After a long night on the drug, he went through a tough phase of the withdrawal the next day. But ibogaine let him put the withdrawal in context: he could change his life if he stayed off drugs. He followed his study treatment with a 12-step program and has been opiate-free ever since he was dosed, in 2011.</p>
<p><q class="center">Because addiction is varied, it&#8217;s hard to say what people will respond best to &mdash; for some, the best approach may be methodone, Suboxone, or just abstinence</q></p>
<p>Parrino, the AATOD president, says that because addiction is varied, it&rsquo;s hard to say what people will respond best to &mdash; for some people, the best approach may be methadone, Suboxone, or abstinence. &#8220;There&rsquo;s no single treatment that works for everybody,&#8221; he says. Ibogaine could be added to this repertoire &mdash; but he wants to see more studies.</p>

<p>In addition to the US ibogaine study, an identical one, using the same procedure, was conducted in New Zealand. (It was also sponsored by MAPS.) That study included 14 patients, and three dropped out before it was finished. Both research groups will submit their results to scientific journals in the coming months. Dr. Geoff Noller, of the New Zealand study, says the preliminary results show the majority of their 11 patients stayed off opiates for a year after one ibogaine treatment. (There are some differences between the trials, most obviously in participants: 70 percent of Noller&rsquo;s patients were addicted to methadone, which is an opiate that&rsquo;s more commonly abused in New Zealand.)</p>

<p>At this point, it&rsquo;s unlikely swaths of addicts will be flocking to places like Mexico to do psychotropic drugs like ibogaine, but ibogaine may hold potential. And what happens after the drug&#8217;s administered may play a crucial role, the experts agree. Take Kevin: in addition to his 12-step program, he says he&rsquo;s avoided situations where he would be around opiates, and he hasn&rsquo;t had many urges to do them again. But he also describes the ibogaine treatment as crucial for his recovery. &#8220;Without it I don&rsquo;t know how I ever would have stopped,&#8221; he says.</p>

<p><em><strong>Correction:</strong> This article originally stated that ibogaine was made a Schedule I substance in 1968. In fact, it was 1970. We regret the error.</em></p>
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					</entry>
			<entry>
			
			<author>
				<name>Thor Benson</name>
			</author>
			
			<title type="html"><![CDATA[The controversial quest to stop climate change by pulling carbon out of the air]]></title>
			<link rel="alternate" type="text/html" href="https://www.theverge.com/2015/8/19/9174589/climate-change-carbon-removal-capture-air" />
			<id>https://www.theverge.com/2015/8/19/9174589/climate-change-carbon-removal-capture-air</id>
			<updated>2015-08-19T12:23:34-04:00</updated>
			<published>2015-08-19T12:23:34-04:00</published>
			<category scheme="https://www.theverge.com" term="Report" /><category scheme="https://www.theverge.com" term="Science" />
							<summary type="html"><![CDATA[Most efforts at combating climate change have focused on reducing carbon emissions or trying to eliminate them, but many climate scientists believe we may have already passed the point of no return. That&#8217;s why Noah Deich wants to pull carbon out of the air. &#8220;Not only can we stop making a mess, we can clean [&#8230;]]]></summary>
			
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<img alt="" data-caption="" data-portal-copyright="&lt;a href=&quot;https://www.flickr.com/photos/otodo/3558890813/in/photolist-6quffr-e8aPVk-4qYkyT-iseeSK-aD78vN-4Maa4-5XaLVQ-4jZkPk-aD76tJ-3bYp9d-4LdVfv-5TP7ZU-deFa29-avLsBH-nievh1-7D16u9-66L6Er-outQMW-wyh4-aWaXH-4Ma9r-ah5bVU-5RD5Ac-aVsdd-aVs3K-aVrUL-a2do73-4i8PwS-4jZnbi-9HWpeT-fTZKRk-4jZkwi-4i8QCN-7uRCiq-aWq6N-aWq1s-aWpUA-aWaSz-aWaML-aW852-7se2pH-vGFyv-e5u77H-avLsnV-iBEcm-4gJRYu-iyNVi-ckNKS-a2gVx-pRYzxb&quot;&gt;otodo (Flickr)&lt;/a&gt;" data-has-syndication-rights="1" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/15469755/3558890813_e0e266ede9_o.0.0.1439942733.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<p>Most efforts at combating climate change have focused on reducing carbon emissions or trying to eliminate them, but many climate scientists believe we may have already passed the point of no return. That&rsquo;s why Noah Deich wants to pull carbon out of the air.</p>
<p><q class="right">&#8220;Not only can we stop making a mess, we can clean it up.&#8221;</q>Deich is the founder of a nonprofit called the Center for Carbon Removal; its goal is to bring together scientists, political figures and leaders in the energy industries to find the best way to remove CO2 from the atmosphere. &#8220;Not only can we stop making a mess, but we can clean it up and hopefully prevent all of the damages scientists expect will happen if we don&rsquo;t clean it up,&#8221; he says.</p>
<p>Carbon removal schemes aren&rsquo;t new, and they aren&rsquo;t entirely supported by the scientific community, either. Some groups of scientists are working on the problem, and documents like the one published by the UN&rsquo;s Intergovernmental Panel on Climate Change urge developing this kind of technology in the future. One major barrier is cost. Technology already exists to remove CO2 from smokestacks at a reasonable price, but taking it out of the air raises the price &mdash; just how much, though, is disputed.</p>

<p>&#8220;It&rsquo;s not a question of if we can take carbon out of the atmosphere, but I think the question is if all of the technologies that can take carbon out of the atmosphere do it in a cost effective, sustainable and scalable way,&#8221; Deich says. He believes we can find a cost effective method.</p>
<p><q class="center">One thing is for sure: the amount of carbon dioxide in the atmosphere is rising</q>One thing is for sure: the amount of carbon dioxide in the atmosphere is rising. Currently, the level of CO2 is just <a href="http://www.climatecentral.org/news/co2-400-ppm-global-record-18965">over 400 parts per million</a> &mdash; so 400 CO2 molecules for every million gas molecules. It doesn&rsquo;t sounds like a lot, but scientists say that small changes in the balance can have major impacts. Concentrations of carbon dioxide are projected to almost double to 750 parts per million by 2100, according to <a href="http://globalchange.mit.edu/files/2014%20Energy%20%26%20Climate%20Outlook.pdf">research from MIT</a>. Those levels are alarmingly high, since carbon dioxide was at <a href="http://www.scientificamerican.com/article/2015-begins-with-co2-above-400-ppm-mark/">280 ppm</a> before the industrial revolution picked up in the late 1700s and early 1800s.</p><p><q class="left">The UN&#8217;s goal for CO2 emissions is currently unrealistic</q>The UN&rsquo;s goal is to keep CO2 from going over 450ppm in the next century, in the hopes of avoiding the likely catastrophic effects of climate change. That goal currently appears unrealistic,<a href="http://www.washingtonpost.com/national/health-science/effects-of-climate-change-irreversible-un-panel-warns-in-report/2014/11/01/2d49aeec-6142-11e4-8b9e-2ccdac31a031_story.html"> thanks to a lack of investment in the technology and the continued global reliance on fossil fuels, according to many climate scientists</a>. <a href="http://www.huffingtonpost.com/2015/02/13/un-climate-deal-draft_n_6677984.html">Deals among members of the United Nations</a> could help, but they will have to be swift and unyielding to prevent catastrophic consequences. The largest industrial nations will not just have to promise to try to cut emissions by large numbers, they will have to meet those goals and even try to exceed them.</p><img src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3980184/4264685098_9183097529_o.0.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="more smokestacks (flickr)" title="more smokestacks (flickr)" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" /><small><em>(<a href="https://www.flickr.com/photos/ben_grey/4264685098/in/photolist-7uRCiq-aWq6N-aWq1s-aWpUA-aWaSz-aWaML-aW852-7se2pH-vGFyv-e5u77H-avLsnV-iBEcm-4gJRYu-iyNVi-ckNKS-a2gVx-pRYzxb-4QgF1w-4k4k2b-s2hVy-4i4HaV-4i8Q9S-4eDSMZ-e5ubjr-x8nMN-8LpcoX-5srrqp-7shZbq-kYFowb-apKvsA-e5qLT-aN3iJZ-4Co2uh-dF6goV-9mBdfC-5gfgXQ-5gaWEB-5gaWzc-5gfgGE-bD5n6f-aD76XL-ah2oWk-dmu143-9D983b-9D6cCZ-5gfgid-oVXJ-7bqi7E-bCeMzL-r5BZ8a">Ben Grey, Flickr</a>) </em></small>
<p>In terms of technological help, a machine made to pull carbon dioxide out of the air is crucial, says Deich. Recently, just such a machine made headlines: it pulls <a href="https://www.minds.com/blog/view/468466376596533248/new-co2-recycler-captures-carbon-dioxide-from-the-atmosphere-and-turns-it-back-into-fuel">CO2 out of the air</a>, processes it and combines it with hydrogen to make hydrocarbons so the CO2 can be used as fuel. There are also ideas for <a href="http://e360.yale.edu/feature/soil_as_carbon_storehouse_new_weapon_in_climate_fight/2744/">storing carbon in soils</a> that can absorb it. &#8220;This is really an untapped area for technology innovation,&#8221; Deich said.</p>
<p><q class="right">Lackner believes his methods could help stop climate change</q>One method for carbon removal, created by Klaus Lackner, who is the director at the Center for Negative Carbon Emissions, uses sodium carbonate and a resin material to suck up carbon from the air like a plant&rsquo;s or tree&rsquo;s leaves do. The resin soaks up the CO2 like a sponge, and the carbon can be removed by adding water in a vacuum sealed container. Then, the CO2 can be pumped underground, in a process called sequestration.</p>
<p>Lackner believes his methods could help stop climate change. He says it&rsquo;s not likely the atmosphere can handle &#8220;800 or 1,000 ppm of CO2, and we will likely get there this century if we don&rsquo;t do anything about it,&#8221; Lackner told <em>The Verge</em>. &#8220;We will need to balance the system out and find a way to get negative emissions.&#8221;</p>

<p>Much of the scientific community doesn&rsquo;t especially care for carbon capture. Many researchers who are working on promoting green energy or planning on capturing the CO2 directly from smoke stacks don&rsquo;t want a technology that lets people pollute as much as they want so it can be captured later, Lackner says. But plenty of fossil fuels are burned without carbon capture &mdash; in planes, ships, and automobiles, for instance &mdash; so we will eventually have to capture what&rsquo;s already in the atmosphere, he says. The real issue is affordability.</p>
<p><q class="left">The real issue is affordability</q>People like Lackner are hopeful that carbon capture can be made cheap quickly. But that may not be possible. For instance, there&rsquo;s <a href="http://web.mit.edu/ebm/www/Publications/NSFJan08.pdf">Sherwood&rsquo;s plot</a>, a graph that shows how much it will cost to handle a certain volume of material based on how diluted it is. It&rsquo;s a <a href="http://www.nap.edu/openbook.php?record_id=2129&amp;page=70">straight line</a> upward for cost as the material is more diluted. CO2 is 300 times more diluted in air than it is in a smoke stack, according to Lackner. With the cost of taking it out of a smokestack running around <a href="http://www.princeton.edu/mae/people/faculty/socolow/12-03-07-Calgary-Summit-keynote.pdf">$80 to $100</a> per ton of CO2, it would conceivably be incredibly expensive to take it out of the air. Most estimates for the cost of open air carbon capture range between $200 per ton and $1,000 per ton of CO2.</p>
<p>Lackner wants to find his way around the plot&rsquo;s skyward trajectory. He agrees with the basic idea behind Sherwood&rsquo;s plot &mdash; that a more dilute substance costs more to capture &mdash; but he thinks he can disrupt the linear growth in cost. The way to do that, according to Lackner, is by not forcing the machine to actively seek out carbon dioxide. His device lets CO2 come to it, instead of grabbing everything around in an attempt to find CO2, as its first step of the process&mdash; think of it as standing in the wind, rather than sucking in large volumes of air. Designs that allow this type of airflow could get the cost down to $5 or $10 per ton of CO2 captured, Lackner says.</p>

<p>But Lackner&rsquo;s estimates sharply contrast what some studies of carbon capture devices, which usually estimate capture&rsquo;s minimum cost as around $200&ndash;$400 per ton. Howard Herzog, a senior research engineer at MIT, was one of the researchers who helped conduct a <a href="http://sequestration.mit.edu/pdf/1012253108full.pdf">2011 study</a> that looked at the cost of capturing carbon from outside air. His team based their research on the devices that would capture carbon from smoke stacks, and using Sherwood&rsquo;s plot, they found an open air machine would likely cost $1,000 per ton of CO2 captured at this point. However, Lackner&rsquo;s device isn&rsquo;t the same as the device used to get CO2 from smokestacks, so this estimate may not directly reflect that cost.</p>
<img src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3980172/Screen_Shot_2015-08-18_at_4.59.08_PM.0.png" alt="sherwood" data-chorus-asset-id="3980172"><small><em>Sherwood&#8217;s plot (<a href="http://web.mit.edu/ebm/www/Publications/NSFJan08.pdf">Gutowski et. al</a>) </em></small>
<p>There are ways that cost can be driven down, but the overall volume of the air that needs to be handled and how diluted the CO2 is makes it an expensive process, Herzog says. &#8220;If you have basically free electricity [for the device], then that changes things, but I just don&rsquo;t see that happening anytime soon,&#8221; he says. One of the biggest issues is how much energy a machine needs to capture carbon, so very cheap electricity will be key. Even technologies that are often called free energy, like solar panels, typically cost at least 12 cents per kilowatt hour &mdash; and that&rsquo;s still too expensive. It&rsquo;s important that the air capture device be running on energy not created by burning much fossil fuels, otherwise you&rsquo;re just &#8220;chasing your tail,&#8221; Herzog says.</p>
<p><q class="left">Cost is the biggest hindrance to carbon capture</q>Cost is the biggest hindrance to carbon capture &mdash; everyone agrees on that, even if they disagree about how expensive it will actually be. Once some groups have built their devices to scale and fully tested them in a large area, the reality of these devices will be a little clearer. Right now, prototypes have only been tried out in test facilities, with little reported but estimated costs and basic efficacy. <a href="http://www.aps.org/policy/reports/assessments/upload/dac2011.pdf">Initial tests</a> show many devices capture at least half the CO2 they come in contact with, but they&rsquo;re still pricey to develop and use. But these devices haven&rsquo;t been tested much, so that&rsquo;s hardly the final word. Proponents of carbon removal devices claim they are a necessity to help clean up our mess &mdash; but necessity doesn&rsquo;t determine a technology&rsquo;s success. As more prototypes are tested, we may actually find out if we can clean up after ourselves &mdash; and at what cost.</p>
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			<entry>
			
			<author>
				<name>Thor Benson</name>
			</author>
			
			<title type="html"><![CDATA[All &#8216;Smiles&#8217;: the history of the 2C designer drug class]]></title>
			<link rel="alternate" type="text/html" href="https://www.theverge.com/2015/7/15/8962743/all-smiles-the-history-of-the-2c-designer-drug-class" />
			<id>https://www.theverge.com/2015/7/15/8962743/all-smiles-the-history-of-the-2c-designer-drug-class</id>
			<updated>2015-07-15T10:00:02-04:00</updated>
			<published>2015-07-15T10:00:02-04:00</published>
			<category scheme="https://www.theverge.com" term="Report" /><category scheme="https://www.theverge.com" term="Science" />
							<summary type="html"><![CDATA[The first time I tried 2C-B, I was at a punk rock show; I threw back the pills as we walked to the venue. 2C-B was both mild and intense, depending on the moment. &#8220;The lights dimmed and brightened, forcing a woman&#8217;s leopard-print coat to feather and contract with the shadows,&#8221; I later wrote of [&#8230;]]]></summary>
			
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<img alt="" data-caption="" data-portal-copyright="Alexsey Kashtelyan" data-has-syndication-rights="1" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/15431448/Shulgin_Image_Benson.0.0.1436897159.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<p>The first time I tried 2C-B, I was at a punk rock show; I threw back the pills as we walked to the venue. 2C-B was both mild and intense, depending on the moment. &#8220;The lights dimmed and brightened, forcing a woman&rsquo;s leopard-print coat to feather and contract with the shadows,&#8221; I later <a href="http://www.vrtxmag.com/articles/wandering-through-dissonance-with-a-happy-death/">wrote of the night</a>. &#8220;An image decorating the wall of a woman with her hands pushed forward seemed to reach out and grab at the crowd.&#8221; I experienced light psychedelic visuals, moments of paranoia, euphoria, and at one point anger, when an idiot playing pool kept getting in the way of the concertgoers. My body felt warm, electric, and sensitive to the touch, and the objects and people I looked at seemed to expand and contract in a moment.</p>
<p><q class="left">The 2C family of drugs has a complex and sometimes controversial past</q>I first heard of the 2C family of drugs when a friend came to visit me while I was living in Portland, Oregon. He was a veteran in the psychedelic drug world, and he told me 2C drugs are closely related to substances like MDMA; I&rsquo;d get a similar effect to MDMA but with increased psychedelic visuals and feelings. There are many versions of 2C drugs, from 2C-I to 2C-B to the infamous 2C-P, which allegedly keeps you high for as long as 24 hours. Each one has its own unique chemical properties and particular effects.</p>
<p>The 2C family of drugs has a complex and sometimes controversial past. They are synthetic psychedelics in the phenylethylamine class. They were first synthesized by the late Alexander Shulgin around 1974, who is known for popularizing MDMA. Like MDMA, 2C drugs were first utilized for therapeutic purposes among Shulgin and his colleagues and later became known as club drugs. No official clinical trials were done, but there was some experimentation. Rumor has it that a German company distributed 2C-B in the 1980s for use as an aphrodisiac called &#8220;<a href="http://psychonautwiki.org/wiki/2C-B">Eros</a>.&#8221; If this is true, there are no records of it.</p>
<p><q class="right">The increased interest in MDMA may revive research on 2C drugs</q>Shulgin and others have long speculated 2Cs could be used for therapeutic purposes, but a lack of basic research creates a catch-22: without any information, there&rsquo;s no reason to conduct a study, says David Nichols, founding president of the Heffter Research Institute, which studies psychedelic drugs<em></em>. 2Cs are known to have certain effects and dangers, but the kinds of trials a scientist would do to get a better understanding of those elements are missing. Because clinical trials are expensive, it&rsquo;s hard to provide enough justification to study this family of drugs in any serious way. That means we don&rsquo;t even know what dosages are dangerous. But an increased level of research interest in MDMA, the 2Cs&rsquo; older cousin, may revive interest in the drugs.</p><img src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3873252/4185695212_f9f0b05027_o.0.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="psychedelic visual" title="psychedelic visual" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p><em><em>(</em></em><a href="https://www.flickr.com/photos/lkaestner/4185695212/in/photolist-7nSMmQ-c2m2ts-2pdCL"><em><em>Lukas K&auml;stner</em></em></a><em><em>) </em></em></p>

<p>When MDMA was banned in the US in 1985, 2C drugs became a quick replacement in the club scene. As was the case for many synthetic drugs, 2C drugs&rsquo; existence wasn&rsquo;t well-known among government officials &mdash; which meant they weren&rsquo;t illegal for some time. The main 2C varieties were eventually named as Schedule 1 drugs and became illegal around 1994. Also, like many synthetic drugs, renegade chemists began creating slightly different versions of the drugs so they could claim to sell a legal version.</p>
<p><q class="center">When MDMA was banned in the US, 2C drugs became a quick replacement</q></p>
<p>Since the 1990s, a lot of other illegal drugs &mdash; MDMA, marijuana, LSD, and psilocybin &mdash; have been more widely studied by the medical research community. The 2C family has been an exception, though. At least in part because of a lack of knowledge around the family, some compounds have caused <a href="http://www.livescience.com/23388-designer-drug-smiles-teen-deaths.html">overdoses</a> that can end in death. Some experts claim the deaths associated with the original 2C varieties <a href="http://blogs.plos.org/takeasdirected/2012/10/03/nbomics-the-science-of-smiles/">should actually be attributed to tainted versions</a> of the drugs, as investigators may have misidentified what kind of 2C it was &mdash; but problems can happen when too much of any 2C is taken. Altered versions of the original 2C types can also be significantly more potent, and one known physiological effect is a dangerously elevated heart rate. Problems can also occur when 2C drugs are taken with other substances.</p>

<p>Overdoses related to the derivative 2C-I-NBOMe have been widely publicized; users apparently often thought they were taking LSD. Some experts told <em>The Verge </em>it&rsquo;s easier to overdose on drugs like 2C-I than it is drugs like MDMA, since it&rsquo;s more potent. But with the correct dosage, 2C-I is typically regarded as being as safe as MDMA among Erowid users &mdash; a group with an interest in psychoactive chemicals.</p>
<p><q class="left">&#8220;Smiles&#8221; is a term the media uses for 2C-I, though I&#8217;ve never heard anyone from the psychedelic community use that name</q>Most people know the family through lurid headlines like this one: &#8220;Johnny Lewis, &lsquo;Smiles,&rsquo; and the Latest Designer Drug Panic,&#8221; a story<a href="http://grantland.com/hollywood-prospectus/johnny-lewis-smiles-and-the-latest-designer-drug-panic/"> from <em>Grantland</em></a> when a <em>Sons of Anarchy</em> actor died in 2012. &#8220;Smiles&#8221; is a term the media has used for 2C-I, though I&rsquo;ve never heard anyone in the psychedelic community refer to the compound that way.</p>
<p>Around 2000, three deaths were recorded related to the 2C-T&ndash;7 derivative. Shulgin, who was still alive at the time, expressed his frustration over what amateur chemists were doing to his promising creation. &#8220;I&rsquo;m disturbed by the fact that you get someone who wants to make a pile of money and doesn&rsquo;t give a damn about the safety or the purity,&#8221; he <a href="http://www.theguardian.com/science/2014/jun/03/alexander-shulgin">told <em>The Guardian</em></a> at the time. &#8220;It&rsquo;s a motivation that I&rsquo;m uncomfortable with. People using psychedelics, I&rsquo;m not uncomfortable with. I consider it a very personal exploration. But I&rsquo;m very disturbed by the overpowering of curiosity with greed.&#8221; Shulgin&rsquo;s creation, which he believed had serious therapeutic potential, became the synthetic killer of its time.</p>
<img src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3873284/142789779_7d6a5ab8a7_o.0.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="pills" title="pills" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p><em><em>(</em></em><a href="https://www.flickr.com/photos/erix/142789779/in/photolist-dBQqK-6eHN2-54dH9T-7YXZBy-8dZbk4-5mbfoe-7yCZy-8e3rVS-5Ya3x-7e7YYi-D3X8F-namCZ-jzZsMe-4xcHp9-9Ti8-8mnDMN-4Jhidb-5YNb7p-3HhCxy-8oXF9y-aZq5vn-pY5U6-5rUYAS-cQjmas-8dZbFR-5QrGsw-oW2aQ-4q3H8v-9KY9Wj-3LbDz-8dZbs8-a2MB7-qhBL-3bmH9J-jNEwz-fQQxg6-buQdLm-5ngkFL-buQdCq-7n4MH9-FqENz-bXb3Ln-9KVkMX-55WXxR-9sS84N-53wpf4-9pT6Uy-7EMyoa-8oXGuG-83NCiK"><em><em>Erich Ferdinand</em></em></a><em><em>)</em></em></p>

<p>MDMA-assisted psychotherapy has shown promise as a treatment for disorders like PTSD and anxiety in clinical studies. Shulgin always believed 2C drugs could provide similar benefits. &#8220;[2C-B] is, in my opinion, one of the most graceful, erotic, sensual, introspective compounds I have ever invented,&#8221; he said <a href="http://www.cognitiveliberty.org/shulgin/adsarchive/2cb.htm">during an interview</a> with the Center for Cognitive Liberty &amp; Ethics in 2003. &#8220;For most people, it is a short-lived and comfortable psychedelic, with neither toxic side effects nor next-day hangover. Its effects are felt very much in the body, as well as in the mind, and thus it has found clinical use as a follow-up to MDMA.&#8221; MDMA could be used to help people identify their problems during therapy &mdash; then 2C-B could be administered to help them open up the &#8220;emotional, intuitive, and archetypal&#8221; areas of the brain to help them solve those problems, Shulgin said.</p>
<p><q class="left">Studying clinical uses would require toxicity studies &mdash; which likely will cost $200,000</q>The main issue with the 2C family of drugs continues to be the void of information on their effects and dangers. Much more research has been done on MDMA than any 2C compound. &#8220;To study any possible clinical uses would require first carrying out toxicity studies, likely at a cost of around $200,000,&#8221; Nichols says. &#8220;To justify that cost to a private investor, one would have to have a good idea that the compound to be studied actually would prove to have beneficial medical effects.&#8221; The evidence isn&rsquo;t there yet.</p>
<p>That&rsquo;s because when 2Cs were born, no one did any major investigations regarding medical uses of the class &mdash; or even toxicity. Even though MDMA and other compounds are relatively under-studied, enough information existed to suggest they might benefit some people. But because no similar studies have been conducted on 2Cs, there&rsquo;s no hint the drugs may have therapeutic benefits.</p>
<p><q class="center">It&#8217;s possible things could change, and once again, MDMA may lead the way </q>Right now, the information void makes for polarized rhetoric &mdash; think of the chasm between the deaths from overdose and Shulgin&rsquo;s hopes. But it&rsquo;s possible to imagine that could change, and once again, MDMA may lead the way. If MDMA-assisted psychotherapy gains acceptance, doctors may consider ways to alter or heighten that therapy with other compounds, says Brad Burge, director of communications and marketing at the Multidisciplinary Association for Psychedelic Studies. And given Shulgin&rsquo;s thoughts on the class, the 2Cs seem like a natural choice for combination therapy. &#8220;That&rsquo;s the future of psychedelic therapy research,&#8221; Burge told <em>The Verge</em>. &#8220;Once MDMA-assisted psychotherapy is legal and approved, therapists and patients will want to know how to maximize these tools.&#8221; Now that MDMA is starting to break free of government restrictions, perhaps Shulgin&rsquo;s dream of using 2C drugs as medicine will be realized.</p>
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					</entry>
			<entry>
			
			<author>
				<name>Thor Benson</name>
			</author>
			
			<title type="html"><![CDATA[Scientists are testing MDMA as a PTSD treatment for veterans]]></title>
			<link rel="alternate" type="text/html" href="https://www.theverge.com/2015/4/24/8471817/mdma-ptsd-therapy-veteran" />
			<id>https://www.theverge.com/2015/4/24/8471817/mdma-ptsd-therapy-veteran</id>
			<updated>2015-04-24T09:30:02-04:00</updated>
			<published>2015-04-24T09:30:02-04:00</published>
			<category scheme="https://www.theverge.com" term="Report" /><category scheme="https://www.theverge.com" term="Science" />
							<summary type="html"><![CDATA[About three years after his discharge from the US Marine Corps, Nicholas Blackston is in an unfamiliar office, starting to feel the effects of an unfamiliar drug: as he watches, an old-fashioned banker&#8217;s lamp in the office suddenly bursts into kaleidoscope fractals. While the MDMA Blackston&#8217;s been dosed with is usually more associated with raves, [&#8230;]]]></summary>
			
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<img alt="" data-caption="" data-portal-copyright=" Nicholas Blackston " data-has-syndication-rights="1" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/13075287/IMG_42412124231569.0.0.1429745584.jpeg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<div class="m-snippet thin"> <p>About three years after his discharge from the US Marine Corps, Nicholas Blackston is in an unfamiliar office, starting to feel the effects of an unfamiliar drug: as he watches, an old-fashioned banker&rsquo;s lamp in the office suddenly bursts into kaleidoscope fractals. While the MDMA Blackston&rsquo;s been dosed with is usually more associated with raves, glow sticks, and rap lyrics, the chemical also has a second life as a medication used to heal psychological wounds.</p> <p> </p> <aside class="float-right"><q>An ideal patient </q></aside>In some ways, Blackston is an ideal patient for MDMA &mdash; and one of a growing number of people with PTSD who are turning to the compound, <a href="http://www.theverge.com/2014/4/29/5594872/ecstatic-states-can-an-illegal-drug-treat-ptsd">as<em> The Verge</em> has previously reported</a>. He wasn&rsquo;t responding to the drugs that are typically prescribed for PTSD, and he has an open mind when it comes to alternative treatments. Blackston <a href="http://www.theverge.com/2015/3/21/8269423/mdma-medical-use-clinical-trial-terminally-ill">is part of a study</a> that&rsquo;s revived interest in the original use of MDMA: therapy.<p> </p> <p>Blackston joined the Marine Corps when he graduated from high school in 2004 &mdash; as the war in Iraq was steadily intensifying. On December 20th, 2006, during his second deployment, Blackston was in the passenger seat of a Humvee in Ramadi, acting as the machine gunner. The Humvee was struck by a rocket-propelled grenade fired by an insurgent. New armor was installed on the driver&rsquo;s side of the truck, but the RPG caused a piece of metal to shoot underneath the driver&rsquo;s window and through the driver&rsquo;s lap. The shrapnel pierced ammo cans at Blackston&rsquo;s feet and caused an explosion. &#8220;I took shrapnel to my butt, legs, and left testicle,&#8221; says Blackston. &#8220;My driver was killed.&#8221;</p> <p>Blackston remembers he had been laughing at some joke when everything became a &#8220;black void.&#8221; The world around him seemed to be moving in slow motion; he felt no fear at the time. &#8220;I was really outside of myself,&#8221; he says. The fear would come later.</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet"> <img data-chorus-asset-id="3632962" alt="blackston self-portrait" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3632962/Reflection_of_Mortality__self_portrait_.0.jpg"> <p class="caption">A self-portrait entitled &#8220;Reflections of Mortality.&#8221; (Blackston)</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet thin"> <p>About six months after leaving Iraq &mdash; but while still in the military &mdash; Blackston discovered he didn&rsquo;t feel like himself. He went to a military clinic in Camp Lejeune, North Carolina, where a computerized test flagged him for post traumatic stress disorder (PTSD). Blackston received the same treatment the majority of veterans with PTSD receive. The military doctors put him on Seroquel, an antipsychotic, and Zoloft, an antidepressant. The talk therapy he received was minimal; he says he had to wait six weeks between hour-long therapy sessions. &#8220;There was just so much time in between that the therapy sessions were pointless, and the medication just makes you feel like a zombie,&#8221; he says.</p> <p> </p> <aside class="float-left"><q>&#8220;The medication just makes you feel like a zombie.&#8221; </q></aside><p>He finished his four years with the Marines in 2008; back home, he began studying at Trident Technical Community College in South Carolina. But the drugs made it harder to focus on his schoolwork &mdash; so he stopped taking them. He tried using marijuana and psychedelic mushrooms instead, which he describes as Band-Aids on his wounds. He had experienced suicidal thoughts. And that was when Blackston came across a study designed to treat PTSD with MDMA. &#8220;I was at the end of my rope. I was ready to try anything,&#8221; he says.</p> <p>Before becoming a participant in the study, which was conducted by the Multidisciplinary Association for Psychedelic Studies (MAPS), applicants have to do psychological tests to confirm they have PTSD and show that they&rsquo;ve been taking prescription drugs that haven&rsquo;t worked. Everything checked out for Blackston.</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet full-image"> <img data-chorus-asset-id="3632954" alt="mdma pills" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3632954/IMG_6260.0.jpg"> <p class="caption">MDMA pills. (MAPS)</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet thin"> <p>Patients like him have three 90-minute meetings with Dr. Michael Mithoefer and his wife Annie to get them oriented, Mithoefer tells <em>The Verge</em>. After that, they begin the MDMA-assisted psychotherapy sessions. The patients come into the office in the morning and take their pill. The therapists stay with the patients for eight hours, during which the session focuses on discussing the experiences that caused patients&rsquo; PTSD. Each MDMA-assisted session is one month apart; the therapists and patient discuss symptoms and general mental health regularly in between sessions over the phone or in person.</p> <p>In the study, participants receive either low-, medium-, or full-dose MDMA &mdash; 30mg, 75mg, or 125mg, respectively. Patients who were in groups with lower doses have the option to receive three full doses one month after their second session; Mithoefer says everyone gets three full-dose sessions. Two months after the final session, an independent psychologist measures where the patient is on the Clinician-Administered PTSD Scale (CAPS). The test is conducted again a year later.</p> <p> </p> <aside class="float-right"><q>It&#8217;s not clear how MDMA may help patients recover</q></aside><p> </p> <p>It&rsquo;s not clear how MDMA may help patients recover from PTSD. Imaging studies of PTSD have shown <a href="http://www.dibs.duke.edu/news/announcements/2012/11/06/ptsd-linked-to-smaller-brain-area-regulating-fear-response/">increased activity in the amygdala</a>, the fear center of the brain, and decreased activity in the prefrontal cortex and in the hippocampus. Essentially, three parts of the brain are operating irregularly, which prevents people with PTSD from processing everyday experiences normally. However, once people take MDMA, there&rsquo;s increased activity in the prefrontal cortex, and decreased activity in the amygdala &mdash; it basically evens out the scale so proper therapy can be done, Mithoefer says.</p> <p>PTSD patients are often &#8220;too aroused or mostly numb&#8221; during therapy without MDMA; the drug helps therapy happen for them &#8220;meaningfully, without being overwhelmed by the fear,&#8221; Mithoefer says.</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet"> <img data-chorus-asset-id="3632968" alt="sketch of blackston" src="https://platform.theverge.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/3632968/IMG_10211561542643.0.jpeg"><p class="caption">Drawing by Blackston, based on what he saw during his MDMA trip. (Blackston)</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet thin"> <p>Whatever the explanation, the results in small trials look promising. A previous study found 10 of 12 patients no longer registered PTSD on their CAPS scores after receiving MDMA-assisted psychotherapy. Mithoefer says his group hasn&rsquo;t fully analyzed the results for the study Blackston participated in. He says the outcomes look similar to the first study so far; analysis will be released in May.</p> <aside class="float-left"><q>&#8220;I saw my whole past completely differently.&#8221;</q></aside><p>As for Blackston, he says MDMA and therapy cured him. He did three 75mg sessions and three full dose sessions, finishing in 2012 &mdash; and no longer registers on the PTSD scale. He views the trial positively. &#8220;I had a profound moment, I guess it felt like a bird&rsquo;s-eye view of how everything went down [in Iraq] and why it happened,&#8221; he says. &#8220;I was a machine gunner. I was supposed to take anyone out before they take us out, and getting hit was my responsibility, and my driver dying weighed a lot on me. I had that guilt for the longest time,&#8221; he says. In therapy, he had a moment where he finally saw the big picture. &#8220;I saw my whole past completely differently,&#8221; he says. &#8220;It no longer became something that was haunting me.&#8221;</p> <p>Blackston says he still has normal anxieties, but he turns to making art to stay relaxed. &#8220;I was so young to have life and death in my hands,&#8221; he says. When he was still suffering from PTSD, he says he feared his own right hand, because that was his shooting hand. Now, he says he uses it to paint.</p> </div><!-- ######## END SNIPPET ######## --><div class="m-snippet full-image p-scalable-video"><!-- CHORUS_VIDEO_EMBED ChorusVideo:44373 --></div><!-- ######## END SNIPPET ######## --><p><br id="1429743759297"></p>
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